A novel array format for monitoring cellular uptake using a photo-cleavable linker for peptide release.
نویسندگان
چکیده
We developed a novel peptide array format incorporating a photo-cleavable linker for monitoring cellular uptake. Model peptides were successfully immobilised via the photo-cleavable linker onto conventional plates and could be released spatiotemporally using UV irradiation. Incorporation of confocal microscopy allowed for detailed real-time monitoring of cellular internalisation of peptides.
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عنوان ژورنال:
- Chemical communications
دوره 49 57 شماره
صفحات -
تاریخ انتشار 2013